If you just want one lens, the 18-200 mm VR will do it.
If you are into landscapes, the 12-24 mm is a killer lens
If you are into shooting close-ups, then the 105 mm VR will be a great choice.
Nikon D300 DX Reviews | Technical Information | Comments | Advice
An all around good lens for the D300 is the Nikkor 18-200mm Lens:
It takes you from decent wide angle, to pretty nice telephoto. It’s like an 18-55mm lens, and a 55-200mm lens combined. This is a nice lens to use for just all around photography in general. If you were doing something particularly, like wide-angle, or macro, then you know you need to get other lenses. Other lenses are available here:
http://www.amazon.com/s/ref=nb_ss_e?url=search-alias%3Delectronics&field-keywords=Nikkor&x=0&y=0
Thanks for reading!
References :
If you just want one lens, the 18-200 mm VR will do it.
If you are into landscapes, the 12-24 mm is a killer lens
If you are into shooting close-ups, then the 105 mm VR will be a great choice.
References :
digiPro